Larval and Acute Oral Toxicity of Calotropis Procera and Ficus Umbellata, Plants Traditionally Used to Treat Hemorrhoids in Benin

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AuteurYOMAKOU, BATO GEORGES G RENE
AuteurGLIMMA, LAURENT
AuteurASSOGBA, FIDELE M
AuteurGLIMMA, BIENVENU
AuteurAHOTON, DJIDENOU
AuteurAKAKPO, BAI HUGUETTE
AuteurAHOUNOU AIKPE, FIFAMIN JUDITH
AuteurYAYI LADEKAN, ELEONORE
AuteurKPOVIESSI, SALOME
AuteurGBENOU, JOACHIM DJIMON
Date d'ajout2026-06-02T16:06:57Z
Date de disponibilite2026-06-02T16:06:57Z
Date de publication2023
Resumen the modern days, investigation of the phytochemical compounds contained in the traditionallyacknowledged medicinal plants have established significant interest in drug research and developmental projects. In addition, phytochemical compounds in plants are compounds delivered by plants having pharmacological or toxicological properties in man and animals. Calotropis procera (Ait.) and Ficus umbellata (Vahl.) are two medicinal plants used in Benin. Their various preparations were used to treat a number of ailments and diseases, including hemorrhoids. Here, before checking their effects on hemorrhoids, toxicity studies were carried out on the decoction of F. umbellata leaves and those of C. procera with and without potash as used in the traditional treatment of hemorrhoids in Benin. Toxicity test results demonstrated tolerance of the leaves to Artemia salina larvae with all their LC50 > 0.10 mg/mL (0.147 for extract of F. umbellata, 0.224 for extract without potash of C. procera and 0.887 for extract with potash of C. procera) and albino rats of the wistar strain in acute oral toxicity at a single dose of 2000 mg/kg body weight. Studies of chronic and sub-chronic toxicity, as well as the anti-inflammatory activity of the extracts, are in prospect
DOI10.12691/ajps-11-2-1
Autre identifiantBECDB-14703
URIhttps://dspace.uac.bj/handle/123456789/12519
Languefr
Fait partie deAmerican Journal of Pharmacological Sciences
SujetMedicinal plants
Sujetextracts
Sujetphytochemistry
Sujettoxicity
Sujetcytotoxicity
TitreLarval and Acute Oral Toxicity of Calotropis Procera and Ficus Umbellata, Plants Traditionally Used to Treat Hemorrhoids in Benin
TypeArticle

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