A Diffuse Bullous Cutaneous Mastocytosis Mimicking a Bullous Toxidermia in a Black Child

Abstract

Abstract We report a 16-month-old black girl received at emergency with a history of generalized and itchy bullous and post-bullous eruption occurred 24 hours after administrating ibuprofen for acute otitis. The diagnosis of bullous toxidermia was retained and the evolution was quickly favorable. She was seen seventy-two hours after leaving hospital for pruritic papulo-vesiculo-bullae located on the head, face, necklines, buttocks, perineum and legs after eating crustacean on the day before. The biopsy of a papulo-bullae lesion led to (after the different stains (hematoxylin, Giemsa, toluidine blue) corroborating with immunohistochemical typing with anti CD117) the diagnosis of bullous cutaneous mastocytosis.