Spasmolytic Effects of Aqueous Extract of Sterculia setigera Delile on Isolated Rat Trachea

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dc.contributor.authorAHOUNOU AÏKPE, Judith Fifamin
dc.contributor.authorHAMADOU, André
dc.contributor.authorOuedraogo, Géoffroy
dc.contributor.authorOuédraogo, Sylvin
dc.contributor.authorGBENOU, J.
dc.contributor.authorDANSOU, HOUNDJOVI PIERRE
dc.date.accessioned2026-06-02T16:06:57Z
dc.date.available2026-06-02T16:06:57Z
dc.date.issued2017
dc.description.abstractThe spasmolytic properties of aqueous extract of Sterculia setigera was tested on Rat isolated trachea. Inhibition of the contraction was observed in presence of the aqueous extract (EC50 = 0.91mg/mL ± 0.02) after a pre contraction of the trachea by acetylcholine (10-5M). In the presence of propranolol (10-6M), the spasmolytic activity of the extract was inhibited. The EC50 value was 0.46mg/mL ± 0,11. The aqueous extract of Sterculia setigera also inhibited contraction induced by KCl (4.10-2 M) with EC50 value = 1.9mg/mL ± 0.48). These results clearly show a relaxing effect of aqueous extract of Sterculia setigera on the trachea isolated from rat. This effect involves at least in part β-adrenergic receptor inhibition.
dc.identifier.otherBECDB-5132
dc.identifier.urihttps://dspace.uac.bj/handle/123456789/4795
dc.language.isofr
dc.relation.ispartofAmerican Scientific Research Journal for Engineering, Technology, and Sciences (ASRJETS)
dc.subjectSterculia setigera
dc.subjectbronchodilatory
dc.subjectspasmolytic
dc.subjectRat trachea.
dc.titleSpasmolytic Effects of Aqueous Extract of Sterculia setigera Delile on Isolated Rat Trachea
dc.typeArticle

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