7. EVALUATION OF THE TOXICITY OF THE ETHANOLIC EXTRACTS OF THE LEAVES OF HEXALOBUS MONOPETALUS ON THE KIDNEYS AND THE LIVER OF WISTAR RATS.

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AuteurBEHANZIN, GBESSOHELE JUSTIN
AuteurSOUHAM, ABDERAMAN B
AuteurAHOKPE, ANGELE MELANIE
Date d'ajout2026-06-02T16:06:57Z
Date de disponibilite2026-06-02T16:06:57Z
Date de publication2018
ResumeThe overall objective of our study is to evaluate the toxicity of ethanolic extracts of Hexalobus monopetalus leaves on the liver and kidney functions of rats in its therapeutic use. Thus, an ethanolic extract of the leaves was made, then a phytochemical screening of this extract. On the one hand, acute toxicity was measured in a 14-day feeding trial in Wistar rats, and on the other hand, a histopathological study of the organs removed was performed. The phytochemical screens of the ethanolic extracts obtained showed the presence of several phytochemical groups with therapeutic activity. Acute toxicity was noted at 3000 and 5000mg / kg PC doses of rats. Histopathological study revealed hepatic pycnosis at a dose of 5000 mg / kg PC in rats. Finally, no renal damage was observed.
DOI10.5281/zenodo.2114569
Autre identifiantBECDB-10617
URIhttps://dspace.uac.bj/handle/123456789/9458
Languefr
Fait partie deInternational Journal of Engineering Technologies and Management Research
SujetHexalobus monopetalus
SujetAcute Toxicity
SujetPycnosis
SujetWistar rats
Sujet.
Titre7. EVALUATION OF THE TOXICITY OF THE ETHANOLIC EXTRACTS OF THE LEAVES OF HEXALOBUS MONOPETALUS ON THE KIDNEYS AND THE LIVER OF WISTAR RATS.
TypeArticle

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