Formulation and Optimization of Matrix Tablets Based on Spirulina and Vitamin C.

Simple item page
AuteurAGBOKPONTO, JANVIER ENGELBERT
AuteurASSANHOU, ASSOGBA GABIN
AuteurGANFON, MEDESSOU YOWEL HABIB
Date d'ajout2026-06-02T16:06:57Z
Date de disponibilite2026-06-02T16:06:57Z
Date de publication2023
ResumeSpirulina is a type of algae widely consumed around the world as a dietary supplement due to its great nutritional potential. However, it does not contain vitamin C, a vital vitamin for the proper functioning of the human body, particularly given its immunostimulant potential. The objective of this work was to formulate sustained release spirulina–vitamin C matrix tablets that would enhance particularly a prolonged release and better absorption of vitamin C. A galenic formula based only on vitamin C was made, and then the proportion of vitamin C was reduced in favor of spirulina powder. The manufactured tablets were then subjected to various pharmacopeial quality control tests. The results of these tests showed a good distribution of the powder mixtures in the formulated tablets (i.e., mass uniformity test) and satisfactory outcomes were found for the content uniformity, disintegration and dissolution tests (with 45 % of vitamin C dissolved after 4 hours). Only the results for the friability test were unsatisfactory, indicating the need to improve the physical properties of the powders before compression. These findings open a new area for developing supplementary dietary.
DOI10.22270/jddt.v13i9.6202
Autre identifiantBECDB-14308
URIhttps://dspace.uac.bj/handle/123456789/12207
Languefr
Fait partie deJournal of Drug Delivery and Therapeutics
SujetSpirulina
SujetVitamin C
SujetMatrix tablet
SujetQuality Control
TitreFormulation and Optimization of Matrix Tablets Based on Spirulina and Vitamin C.
TypeArticle

Files

Collections

Articles