Phytochemical screening, anti-inflammatory and immunomodulatory activities of Acanthospermum hispidum and Croton zambesicus collected in the Republic of Benin

Simple item page
AuteurLOKOSSOU, ADJIMON GBENAKPON GATIEN
AuteurKPODJI, PAULIN
AuteurDOUGNON, TAMEGNON VICTORIEN
AuteurBABA MOUSSA, LAMINE SAID
Date d'ajout2026-06-02T16:06:57Z
Date de disponibilite2026-06-02T16:06:57Z
Date de publication2023
ResumeThis study aims to characterize chemical groups of metabolites in extracts of Acanthospermum hispidum and Croton zambesicus, and to evaluate their anti-inflammatory activities and their immunomodulatory effect on two pro-inflammatory cytokines (TNFα and IL6). The phytochemical screening was done on the powders of both plants by staining and precipitation reactions. Anti-inflammatory activity was performed in vivo on rat paw edema induced by 2% formalin and immunomodulatory activity was performed in vitro on rat Peripheral Blood Mononuclear Cells (PBMC) stimulated by Lipopolysaccharide (LPS). The leaves of the plants contained important chemical groups such as: cachectic tannins, flavonoids, terpenes, saponosides and quinones. The ethanolic extracts of the two plants studied showed good anti-inflammatory activity by reducing the volume of the rat paw edema induced by 2% formalin and by inhibiting the production of TNFα, IL6 by PBMC of rats stimulated by LPS.
DOI10.5897/JMPR2021.7145
Autre identifiantBECDB-12689
URIhttps://dspace.uac.bj/handle/123456789/10947
Languefr
Fait partie deJournal of Medicinal Plants Research
SujetAcanthospermum hispidum
SujetCroton zambesicus
Sujetextracts
Sujetphytochemical screening
Sujetbiological activities
TitrePhytochemical screening, anti-inflammatory and immunomodulatory activities of Acanthospermum hispidum and Croton zambesicus collected in the Republic of Benin
TypeArticle

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
6d5710e03e3e5140e512ff1e1975a1c7.pdf
Size:
1.01 MB
Format:
Adobe Portable Document Format
Download

Collections

Articles