Antipyretic and Antianemic Activities of Three Anti-malaria Recipes from South Benin on Wistar Rats

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AuteurMEDOATINSA, SEINDE E
AuteurAGBANGNAN, DOSSA COKOU PASCAL
AuteurATCHADE, SOSSA PASCAL
AuteurBOGNINOU AGBIDINOUKOUN, G SOPHIE REINE
AuteurDOSSEH, KOSSIVI
AuteurKPATCHA, TCHAZOU
AuteurAGBONON, AMEGNONA
AuteurAHISSOU, HYACINTHE
AuteurSOHOUNHLOUE, KOKO CODJO DOMINIQUE
Date d'ajout2026-06-02T16:06:57Z
Date de disponibilite2026-06-02T16:06:57Z
Date de publication2017
ResumeThe present study aims to evaluate "in vivo" the acute toxicity, antipyretic and antianemic activities of three plant recipes used in the treatment of malaria in southern Benin lake cities on Wistar rats. We note the presence of saponosides, phenolic compounds, sterols and terpenes in the recipes studied. The toxicity evaluation of the extracts revealed that they are practically non-toxic (LD50> 5g/kg body weight) according to the Hodge and Sterner classification. All the extracts investigated contain antipyretic molecules but only two extracts (aqueous extract obtain by decoction of the child's recipe: 36.07 ± 0.48°C, hydroethanolic macerated of the adult’s recipe: 36.07 ± 0.33°C) showed significant antipyretic activity, similar to that of aspirin (36.03 ± 0.25°C) used as reference molecule in the present study. After evaluating the antianemic activity, we note that the extracts are not hemolytic.
DOI10.12691/ajps-5-3-1
Autre identifiantBECDB-4065
URIhttps://dspace.uac.bj/handle/123456789/3898
Languefr
Fait partie deAmerican Journal of Pharmacological Sciences
Sujettoxicity
Sujetantipyretic
Sujetantianemic
Sujetmétabolites
Sujetplants
SujetMalaria
TitreAntipyretic and Antianemic Activities of Three Anti-malaria Recipes from South Benin on Wistar Rats
TypeArticle

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