GENETIC POLYMORPHISM OF PARAOXONASE 3 GENE ALA99ALA IN ADJAANDMAHIETHNIC GROUPS IN BENIN..

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AuteurMISSIHOUN, ANTOINE ABEL HOUMENOU
AuteurSEGBO, JULIEN AUGUSTIN GAETAN
AuteurAGBANGLA, CLEMENT
Date d'ajout2026-06-02T16:06:57Z
Date de disponibilite2026-06-02T16:06:57Z
Date de publication2017
ResumeIntroduction:The paraoxonase has anti-atherogenic activity which may be altered by the coding gene polymorphisms. The purpose of this study was to assess the genotypic distribution and allelic frequencies in paraoxonase 3 gene Ala99Ala polymorphism in Beninese Adjaand Mahi ethnic groups. Materials and methods:The paraoxonase 3 gene Ala99Ala polymorphism of 144 subjects of Beninese AdjaandMahi ethnic groups was studied using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism technique and compared with that in Beninese Abomey-Calavipopulationand others world populations. Results:The alleles A and G frequencies were 67.0percent and 33.0 percent respectively ofAdjaethnic group; and 66.0 percent and 34.0percentrespectively ofMahi ethnic group. There were no significant ethnic differences for these allelic frequencies between these two ethnic groups. Conclusion:The genotypic distribution and allelic frequenciesof paraoxonase 3 gene Ala99Ala polymorphism in BenineseAdjaand Mahi ethnic groups were significantly different from those in BenineseAbomey-Calavipopulationand in others world populations respectively.
DOI10.21474/IJAR01/2768
Autre identifiantBECDB-4944
URIhttps://dspace.uac.bj/handle/123456789/4627
Languefr
Fait partie deInternational Journal of Advanced Research (IJAR)
SujetSingle Nucleotide Polymorphism
Sujetgene
Sujetdistribution
Sujetpopulation
TitreGENETIC POLYMORPHISM OF PARAOXONASE 3 GENE ALA99ALA IN ADJAANDMAHIETHNIC GROUPS IN BENIN..
TypeArticle

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