Phytochemical Analysis and Bioactivities Studies of Fresh Leaves and Flowers from C. roseus, L. multiflora and P. amarus, Beninese Medicinal Plants Used Against Diabetes

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AuteurKOUDJINA, SIMPLICE
AuteurHOUNGBEME, ALBAN GOUTON
AuteurAGBOGBA, ISRAEL DOSSOU PAULIN
AuteurATOHOUN, YACOLE GUY SYLVAIN
AuteurGBENOU, JOACHIM DJIMON
Date d'ajout2026-06-02T16:06:57Z
Date de disponibilite2026-06-02T16:06:57Z
Date de publication2023
ResumeTraditional herbal medicines make up a large part of drug use. This work addressed an area of public health, the fight against diabetes. The present study aimed to carry out qualitative and quantitative screening of the secondary metabolites of extracts from the leaves and flowers of plants such as Catharanthus roseus, Lippia multiflora and Phyllanthus amarus, and to evaluate the antioxidant activity in their aqueous and ethanolic extracts, their larval toxicity and then to predict the antidiabetic activity. The results showed that its plants have in their various extracts some secondary metabolites such as alkaloids, tannins, flavonoids, coumarins, terpenoids, phenolic compounds, steroids, etc responsible for several interesting pharmaceutical activities. These medicinal plants showed a higher quantity of polyphenols in the hydro-ethanolic extracts, with levels of 60.65±0.13; 44.40±1.43 and 67.11±0.39 mg.eq/g respectively for C. roseus, L. multiflora and P. amarus and also a higher antioxidant potential for L. multiflora and P. amarus than the standard Vitamin C, with IC50 equal to 0.53 and 0.52 mg/mL respectively. Extracts are not toxic against larvae. These results are an important indicator of the hypoglycemic and anti-diabetic activity and confirmed the potential for use of these plants by the population in the fight against diabetes.
DOI10.11648/j.ijpc.20230905.11
Autre identifiantBECDB-16840
URIhttps://dspace.uac.bj/handle/123456789/14074
Languefr
Fait partie deInternational Journal of Pharmacy and Chemistry
SujetPhytochemical Analysis
Sujetanti-diabetic
SujetAntioxidant Potential
SujetHydro-Ethanolic Extracts
TitrePhytochemical Analysis and Bioactivities Studies of Fresh Leaves and Flowers from C. roseus, L. multiflora and P. amarus, Beninese Medicinal Plants Used Against Diabetes
TypeArticle

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