[Risk of HIV-1 or 2 infection associated with transfusion in Benin]
| Auteur | ZOHOUN, ALBAN GILDAS COMLAN | |
| Auteur | LAFIA, EDGARD | |
| Auteur | HOUINATO, DISMAND | |
| Auteur | ANAGONOU YEHOUENOU, SEVERIN | |
| Date d'ajout | 2026-06-02T16:06:57Z | |
| Date de disponibilite | 2026-06-02T16:06:57Z | |
| Date de publication | 2004 | |
| Resume | OBJECTIVE: To evaluate the residual risk of transmission of HIV 1/2 infection through transfusion of seronegative blood. METHODS: This study was carried out between January and July 2000. It was based on eight hundred and twenty-one (821) blood donors screened negative for HIV antibodies by ELISA using Vironostika Uni-form II plus 0 (Organon Teknika). 675 (82.2%) were men and 146 (17.8%) women all aged between 18 and 56 years with a mean age of 25.5 +/- 7.8 years. Serum aliquots of these seronegative blood donor were frozen and further tested with two tests: Enzymun-Test HIV Combi (Roche Immunodiagnostics) and Murex HIV Antigen Mab (Murex). RESULTS: Twenty six out of 821 (3.2%) seronegative specimens were repeatedly reactive for Enzymun-test. All were tested negative once again for anti-HIV antibodies by ELISA using Vironostika Uni-form II/plus 0. Out of these 26, only one was repeatedly reactive for Murex. For further analysis of the 25 donors tested negative for Murex, only 9 came back for another donation five months later. All of them were tested negative for anti-HIV antibodies by ELISA (Vironostika). CONCLUSION: Our study shows the existence of residual risk of transmission of HIV1/2 infection associated with transfusion of seronegative blood donors. This risk was higher in our countries compared with industrialised nations. Therefore implementing strategies should be a priority to avoid the residual risk and improve blood transfusion safety. | |
| Autre identifiant | BECDB-2414 | |
| URI | https://dspace.uac.bj/handle/123456789/2452 | |
| Langue | fr | |
| Fait partie de | Bulletin De La Societe De Pathologie Exotique (1990) | |
| Sujet | Risk | |
| Sujet | HIV-1 or 2 | |
| Sujet | Associated | |
| Sujet | Transfusion | |
| Titre | [Risk of HIV-1 or 2 infection associated with transfusion in Benin] | |
| Type | Article |