New therapeutic precursors isolated from Arbus precatorius (Fabaceae) a plant used against infections in Benin

AuteurTOKOUDAGBA, KOSSI JEAN MARIE DENIS
AuteurNDOYE, IDRISSA
AuteurGLINMA, BIENVENU
AuteurHOUNGBEME, ALBAN GOUTON
AuteurGANFON, HABIB
AuteurGBAGUIDI, AHOKANNOU FERNAND
Date d'ajout2026-06-02T16:06:57Z
Date de disponibilite2026-06-02T16:06:57Z
Date de publication2023
ResumeWe have contributed to the valorization of a flora plant of beninese used traditionally in antibacterial infections. We have prepared hydroethanolic extract from powdered dried leaves of Arbrus precatorus (Fabaceae). We did a split bioguided from the crude hydro-ethanolic extract. We have isolated and purified by the series of methods chromatography two flavonoids from the active methanolic fraction of the crude hydro-ethanolic extract of the dried leaves of A. precatorius. The spectrometric analyzes carried out, namely mass spectrometry, proton and carbon nuclear magnetic resonance, made it possible to identify the following molecules. These are 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4-oxo-4H-chromen-3-yl acetate and (E)-2-(4-methoxybenzylidene)-5,7-dihydroxy-2,3-dihydroinden-1-one. The added value of the work lies in the fact that these two molecules have never been identified before in this plant and therefore constitute an avenue for developing a therapeutic arsenal to fight recurrent microbial infections.
Autre identifiantBECDB-13328
URIhttps://dspace.uac.bj/handle/123456789/11437
Languefr
Fait partie deThe Pharmaceutical and Chemical Journal
Sujetisolation
Sujetchromatographic methods
Sujetspectrometric analyzes
TitreNew therapeutic precursors isolated from Arbus precatorius (Fabaceae) a plant used against infections in Benin
TypeArticle

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